bactrim and tattoos
In rats, oral doses of either 533 mg/kg sulfamethoxazole or 200 mg/kg trimethoprim produced teratologic effects manifested mainly as cleft palates. Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Most infections can be treated within a week with antibiotics. If your dose is different, do not change it unless your doctor tells you to do so. Trimethoprim is 2,4-diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine. * A total daily dose of 10 to 15 mg/kg was sufficient in 10 adult patients with normal renal function in a published literature. 11. Bactrim stays in your system for about 2 days after a dose is taken. They can let you know whether the medications are safe to take with G6PD deficiency. 9. sore throat. doctor said i should try for 7 days if i can but 6 if it looks healed could work. Sulfamethoxazole and trimethoprim are are both antibiotics that treat different types of infection caused by bacteria. Copyright 1996-2023 Drugs.com. One of 3 rat studies showed cleft palate at doses approximately 5 times the recommended human dose on a body surface area basis; the other 2 studies did not show teratogenicity at similar doses. An official website of the United States government. The trimethoprim component of BACTRIM may cause hyperkalemia when administered to patients with underlying disorders of potassium metabolism, with renal insufficiency or when given concomitantly with drugs known to induce hyperkalemia, such as angiotensin converting enzyme inhibitors. Seven key questions to consider. Minor bumps and rashes can usually be managed at home with antibacterial ointment, proper cleaning, and rest. if you use a blood thinner (such as warfarin) and you have routine "INR" or prothrombin time tests. To help clear up your infection completely, keep using this medicine for the full time of treatment, even if you begin to feel better after a few days. If you have a condition like these, it's understandable to worry that disclosing it to your artist might result in being refused service. This interaction should be kept in mind when BACTRIM is given to patients already on anticoagulant therapy, and the coagulation time should be reassessed. However, though rare, its possible to get a condition such as hepatitis or HIV from a tattoo needle. This is one of the major risks you should be aware of before getting a new piercing or tattoo. If you have G6PD deficiency, you shouldn't take antibiotics known as sulfa drugs. Monitor for the total daily intake of propylene glycol from all sources and for acid-base disturbances. A tattoo blowout looks like your tattoo is bleeding or blurry outside the lines. Some epidemiologic studies suggest that exposure to BACTRIM during pregnancy may be associated with an increased risk of congenital malformations, particularly neural tube defects, cardiovascular malformations, urinary tract defects, oral clefts, and club foot. Peritoneal dialysis is not effective and hemodialysis is only moderately effective in eliminating trimethoprim and sulfamethoxazole. Local reaction, pain and slight irritation on intravenous (IV) administration are infrequent. Blood Thinners:If you are taking any kind of medication to thin your blood, you'll want to inform your artist beforehand, and probably alsoconsult your doctor. Skin and soft tissue infections. Some people recommend removing all legumes (such as beans, peas, lentils, or peanuts) from your diet. In the literature, a single case of toxic delirium has been reported after concomitant intake of BACTRIM and amantadine (an OCT2 substrate). In some cases, your skin may just be irritated because of the needle, especially if you have sensitive skin. Additional monitoring of blood glucose may be warranted. Careful medical history is necessary since CDAD has been reported to occur over two months after the administration of antibacterial agents. There are reported cases of henna triggering hemolytic crises in people with G6PD deficiency. You should also avoid quinolone antibiotics. The presence of 10 mg percent sulfamethoxazole in plasma decreases the protein binding of trimethoprim by an insignificant degree; trimethoprim does not influence the protein binding of sulfamethoxazole. Can I Work Out With a New Piercing or Tattoo? See additional information. It seemed to be missing beats and stopping at times. Life threatening hyperkalemia and acidosis secondary to trimethoprimsulfamethoxazole treatment. Drug information provided by: Merative, Micromedex. Your doctor may adjust this dose if needed. If your tissue has died due to the infection (necrosis), surgery may be needed to remove it. To provide you with the most relevant and helpful information, and understand which The Answer May Surprise You. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Increased digoxin blood levels can occur with concomitant BACTRIM therapy, especially in elderly patients. 4. Both trimethoprim and sulfamethoxazole exist in the blood as unbound, protein-bound and metabolized forms; sulfamethoxazole also exists as the conjugated form. Antimicrob Agents Chemother. If BACTRIM is used during pregnancy, or if the patient becomes pregnant while taking this drug, the patient should be advised of the potential hazards to the fetus [see Use In Specific Populations]. Pharmacology of Intravenous Trimethoprim-Sulfamethoxazole in Children and Adults. BACTRIM contains benzyl alcohol as a preservative. Fatalities associated with the administration of sulfonamides, have occurred due to severe reactions, including, Stevens-Johnson Syndrome, toxic epidermal necrolysis, fulminant hepatic necrosis, agranulocytosis, aplastic anemia and other blood dyscrasias. Your doctor may take a swab of the area or lance a pus pocket (if one is present) to see what bacteria or virus is causing the infection. Bactrim belongs to the class of medicines known as antibiotics. You should not take Bactrim if you are pregnant or breastfeeding. Keep scrolling to learn why it's necessary, what conditions and medications you need to mention, and what happens if they turn you away. Pyrexia, hematuria and crystalluria may be noted. The pharmacokinetics of sulfamethoxazole 800 mg and trimethoprim 160 mg were studied in six geriatric subjects (mean age: 78.6 years) and six young healthy subjects (mean age: 29.3 years) using a non-US approved formulation. You can learn more about how we ensure our content is accurate and current by reading our. Portions of this document last updated: Feb. 01, 2023. This content does not have an English version. RxList does not provide medical advice, diagnosis or treatment. Because of the potential risk of bilirubin displacement and kernicterus on the breastfed child [see CONTRAINDICATIONS], advise women to avoid breastfeeding during treatment with BACTRIM. Mycobacterium fortuitum cutaneous infection from amateur tattoo. Complete the full course as prescribed (unless instructed not to do so by your doctor) to reduce the risk of resistant bacteria developing. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Marinella MA. 1, pp. Verywell Health's content is for informational and educational purposes only. In the U.S. general population, the estimated background risk of major birth defects and miscarriage in clinically recognized pregnancies is 2% to 4% and 15% to 20%, respectively. If CDAD is suspected or confirmed, ongoing antibacterial use not directed against C. difficile may need to be discontinued. In a separate survey, Brumfitt and Pursell also found no congenital abnormalities in 35 children whose mothers had received oral trimethoprim and sulfamethoxazole at the time of conception or shortly thereafter. 2001;14(5):410-414. BACTRIM is available as an injection containing 80 mg/mL of sulfamethoxazole and 16 mg/mL of trimethoprim in 10 mL single-dose and 30 mL multiple-dose vials. Swallow tablets with a big glass of water. If you begin to feel feverish and experience abnormal oozing or scabbing around the tattooed area, see a doctor. Areola micropigmentation: Information for patients. For specific information regarding susceptibility test interpretive criteria, and associated test methods and quality control standards recognized by FDA for this drug, please see https://www.fda.gov/STIC. Bactrim should be discontinued at the first sign of a skin rash or any other worrying side effect. It does not treat viral infections (e.g., the common cold). Ngan V. (2019). The patient was treated with a 2-month course of oral trimethoprim-sulfamethoxazole (160mg/800mg twice daily) and ciprofloxacin (250 mg twice daily), with clinical improvement at follow up after three weeks of the antibiotic regimen. One in five U.S. adults now has a tattoo. Brand names: Bactrim, Bactrim DS Children 2 months of age and olderDose is based on body size and must be determined by your doctor. Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Severe cases of thrombocytopenia that are fatal or life threatening have been reported. sharing sensitive information, make sure youre on a federal Monitor therapeutic response and adjust dose of TCA accordingly. BACTRIM contains propylene glycol as a solvent (40% v/v). What's Really in Tattoo Ink? Should not be used in pregnant or lactating women or babies less than two months old. Concurrent administration is contraindicated, Elevated plasma concentrations of dofetilide have been reported following concurrent administration of trimethoprim and dofetilide. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Pharmacokinetics parameters for sulfamethoxazole were similar for geriatric subjects and younger adult subjects. Discontinue BACTRIM if a significant reduction in the count of any formed blood element is noted. government site. Medically reviewed by Carmen Fookes, BPharm. Learning how to choose a good tattoo artist and take care of your tattoo are crucial to making sure that your tattoo heals well, doesnt get infected, and looks the way you want it to. If need be I can probably reschedule the tattoo appt. Amber Yates, MD, is a board-certified pediatric hematologist and a practicing physician at Baylor College of Medicine. Excretion of trimethoprim and sulfamethoxazole is primarily by the kidneys through both glomerular filtration and tubular secretion. Medicines that interact with Bactrim may either decrease its effect, affect how long it works, increase side effects, or have less of an effect when taken with Bactrim. 2016 Oct 7;113(40):665-671. doi: 10.3238/arztebl.2016.0665. (2015). Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use bactrim only for the indication prescribed. If you stop taking this medicine too soon, your symptoms may return. Trimethoprim-induced hyperkalemia: An analysis of reported cases. Included as part of the PRECAUTIONS section. It belongs to the class of medications known as sulfonamide antibiotics. Cases of interactions with other OCT2 substrates, memantine and metformin, have also been reported. Chen CC, Chen SY, Chen YS, Lo CY, Cheng PW. Is Aquaphor Recommended After Getting a Tattoo? However, the dose is usually not more than 1600 mg of sulfamethoxazole and 320 mg of trimethoprim per day. Some epidemiologic studies suggest that exposure to BACTRIM during pregnancy may be associated with an increased risk of congenital malformations, particularly neural tube defects, cardiovascular abnormalities, urinary tract defects, oral clefts, and club foot (see Human Data). Children 2 months of age and olderDose is based on body weight and must be determined by your doctor. You should also see a doctor if you experience uncomfortable itching around the tattooed area or if the area is oozing pus or fluid. Instruct patients to maintain an adequate fluid intake in order to prevent crystalluria and stone formation. Treatment with antibacterial agents alters the normal flora of the colon leading to overgrowth of C. difficile. J. Nephrol. Kosoglou T, Rocci ML Jr, Vlasses PH. Version: 11.02. Store at room temperature (15C 30C or 59F 86F). Increased plasma concentrations of dofetilide may cause serious ventricular arrhythmias associated with QT interval prolongation, including torsade de pointes, Closely monitor for clinical and ECG signs of procainamide toxicity and/or procainamide plasma concentration if available. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Lastly, outcome measures varied between studies, limiting cross-study comparisons. These steady-state levels were achieved after three days of drug administration. 2018;11(11):CD009435. Alternatively, other epidemiologic studies did not detect statistically significant associations between BACTRIM exposure and specific malformations. 10. If MRSA causes an abscess, your doctor may drain it instead of giving you antibiotics. Suvanasuthi S, Wongpraparut C, Pattanaprichakul P, Bunyaratavej S. Nagore E, Ramos P, Botella-Estrada R, Ramos-Nguez JA, Sanmartn O, Castejn P. Acta Derm Venereol. Remember, people don't turn down a paying client for no reason. Sulfonamides, including sulfonamide-containing products such as BACTRIM, should be discontinued at the first appearance of skin rash or any sign of adverse reaction. Perform urinalyses with careful microscopic examination and renal function tests during therapy, particularly for those patients with impaired renal function. However, the healing process can take upward of, Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. With basic care and good hygiene, most new tattoos heal within a few weeks, but some people may develop an infection that requires medical attention. It happens when ink is injected too deep in the skin. Bactrim (sulfamethoxazole and trimethoprim) and Keflex (cephalexin) are antibiotics prescribed to treat bacterial infections. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Do NOT mix Bactrim in 5% dextrose in water with drugs or solutions in the same container. American Society for Microbiology, Washington, D.C. 1980; Vol. include protected health information. If signs of bone marrow depression occur, the patient should be given leucovorin 5 to 15 mg daily until normal hematopoiesis is restored. (twice a day). DO NOT REFRIGERATE. See your doctor if you experience one or more of the following: A staph infection is one type of infection you might get with a tattoo. Clinical Pharmacology of Intravenously Administered Trimethoprim-Sulfamethoxazole. Last updated on Oct 18, 2021. MeSH Antivir Ther. Increased sulfamethoxazole blood levels may occur in patients who are also receiving indomethacin. Nitrofurantoin and dapsone are additional antibiotics to avoid. Review/update the Distributed by: Sun Pharmaceutical Industries, Inc. Cranbury, NJ 08512. Weighing 16 kg2 teaspoonfuls (10 mL) or 1 tablet 4 times a day for 14 to 21 days. This medicine is available only with your doctor's prescription. In vivo micronucleus assays were positive following oral administration of sulfamethoxazole/trimethoprim. Drug-induced uveitis. Children younger than 2 months of ageUse is not recommended. Was taking bactrim ds for 6 days for skin infection. Bactrim is a combination antibiotic used to treat infections such as those affecting the ear, urinary tract, lungs, or gastrointestinal tract. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Bactrim only for the indication prescribed. AIDS patients may not tolerate or respond to BACTRIM in the same manner as non-AIDS patients. Hence, there is potential for an additive myelotoxicity when coadministered. Patients should follow their doctor's instructions and take all of the Bactrim prescribed. lower back or side pain. Moh R, et al. The base PPD is colourless and requires oxygen for it to become a dye, thus PPD hair dyes . Bactrim may also be prescribed to children over 2 months old, and the dosage is based on the childs weight. Take Bactrim exactly as prescribed by your doctor. Escherichia coliKlebsiella speciesEnterobacter speciesMorganella morganiiProteus mirabilisProteus vulgarisShigella flexneriShigella sonnei. Sulfamethoxazole inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA). 2015;48:76-87. doi:10.1159/000369189, Costa CS, Bagatin E, Martimbianco ALC, et al. Rx only. You may be having an allergic reaction to the ink. Tattoo-associated nontuberculous mycobacterial skin infections multiple states, 2011-2012. Karen L. Hudson is a tattoo artist and contributing writer for Byrdie. Revised 04/2021. Generic name: sulfamethoxazole and trimethoprim [SUL-fa-meth-OX-a-zole-and-trye-METH-oh-prim] Safrin S, Lee BL, Sande MA. Cough, shortness of breath, and pulmonary infiltrates are hypersensitivity reactions of the respiratory tract that have been reported in association with sulfonamide treatment. . And as far as I know it shouldn't have an effect on the tattooing or healing process. Universal precautions for preventing transmission of bloodborne infections. Click here for an email preview. Increased digoxin blood levels can occur with concomitant BACTRIM therapy, especially in elderly patients. BACTRIM, specifically the trimethoprim component, can interfere with a serum methotrexate assay as determined by the competitive binding protein technique (CBPA) when a bacterial dihydrofolate reductase is used as the binding protein. BACTRIM may cause fetal harm if administered to a pregnant woman. Also, although an artist has the right to refuse service to a potential client based on health reasons, you also have the right to take your business elsewhere if you feel the artist was in error or being unfair. and transmitted securely. Weighing 30 kg3 teaspoonfuls (15 mL) of oral liquid or 1 tablet 2 times a day for 10 days. nausea. Tattoo dry healing is an acceptable part of a tattoo aftercare routine as long as you follow all other aftercare instructions closely. Patients who are slow acetylators may be more prone to idiosyncratic reactions to sulfonamides. No interference occurs, however, if methotrexate is measured by a radioimmunoassay (RIA). 7 Things You Should Avoid If You Have G6PD Deficiency. Yet several antibiotics can cause red blood cells to break down. The "DS" form means double strength. If this occurs, patients should contact their physician as soon as possible. Complete blood counts should be done frequently in patients receiving sulfonamides. Last medically reviewed on June 10, 2021. How Long Does It Take a Tattoo to Fully Heal? Drug class: Sulfonamides. information submitted for this request. You may need blood and urine tests, and this medicine may be stopped based on the results. There are reported cases of henna . May lower blood sugar levels in people without diabetes. May be taken with or without food. DOI: Mekaru S. (2011). Speak to your doctor about how drug interactions should be managed. While there are no large, prospective, well-controlled studies in pregnant women and their babies, some retrospective epidemiologic studies suggest an association between first trimester exposure to BACTRIM with an increased risk of congenital malformations, particularly neural tube defects, cardiovascular abnormalities, urinary tract defects, oral clefts, and club foot. In vitro reverse mutation bacterial tests according to the standard protocol have not been performed with sulfamethoxazole and trimethoprim in combination. Kluger N. Contraindications for tattooing. Sun Pharmaceutical Industries, Inc. doi:10.5863/1551-6776-22.6.471, Feghaly J, Al Hout AR, Mercieca Balbi M. Aspirin safety in glucose-6-phosphate dehydrogenase deficiency patients with acute coronary syndrome undergoing percutaneous coronary intervention. LeBlanc PM, et al. In general, you should do the following to make sure the area heals properly: Once the tattooed area starts to form into scabs, use a moisturizer or lotion to keep your skin from getting too dry or damaged. Healthline only shows you brands and products that we stand behind. BACTRIM (sulfamethoxazole and trimethoprim) injection is supplied as follows: 10-mL Vials, containing 160 mg trimethoprim (16 mg/mL) and 800 mg sulfamethoxazole (80 mg/mL) for infusion with 5% dextrose in water. What Type of Cancer Causes Low Hemoglobin (Anemia)? Septra and Bactrim (sulfamethoxazole-trimethoprim) are some common brand names you might encounter. Bactrim is a prescription medicine used to treat ear infections, urinary tract infections, bronchitis, traveler's diarrhea, shigellosis, and Pneumocystis jiroveci pneumonia. Sulfamethoxazole is an inhibitor of CYP2C9. J Infect Dis. However, after normalizing by body weight, the apparent total body clearance of trimethoprim was on average 19% lower in geriatric subjects compared with young adult subjects. Acid-fast bacilli culture identified Mycobacterium fortuitum complex. But getting a tattoo does carry some risk: Inserting an ink-covered needle into your skin has the potential to introduce foreign matter or infections into your body. Zidovudine and BACTRIM are known to induce hematological abnormalities. Privacy Policy. the unsubscribe link in the e-mail. Make sure you ask your tattoo artist what ingredients their inks contain. Because of this potential complication, experts recommend extra precautions. Antibiotics: Disclose all antibiotics to your tattoo artist, and . This means that oxygen-carrying red blood cells break down too fast (called hemolysis), leading to a lack of red blood cells. If you are a Mayo Clinic patient, this could Simple infections confined to the skin and underlying superficial soft tissues generally respond well to outpatient management. methicillin-resistant Staphylococcus aureus, Total Daily Dose (based on trimethoprim content), 15-20 mg/kg (in 3 or 4 equally divided doses), 8-10 mg/kg (in 2 to 4 equally divided doses). This ointment gets its moisturizing powers mainly from petrolatum, lanolin, and glycerin. Ask your healthcare professional how you should dispose of any medicine you do not use. It is safe to take if you are allergic to Penicillin. Acidification of the urine will increase renal elimination of trimethoprim. Severe skin reactions, generalized bone marrow suppression [see WARNINGS AND PRECAUTIONS, ADVERSE REACTIONS], a specific decrease in platelets (with or without purpura), and hyperkalemia are the most frequently reported severe adverse reactions in elderly patients. Amber Yates, MD, is a board-certified pediatric hematologist and a practicing physician at Baylor College of Medicine. Tattoo infections are usually easy to treat and even easier to prevent. We comply with the HONcode standard for trustworthy health information. Bad infections may result in long-term antibiotic care, but usually they wont cause any long-lasting health problems. If youre allergic to any of the ingredients, ask for a different ink or avoid getting a tattoo altogether. Yes, people still use mothballs, mainly to get rid of moths and other insects. JAMA. May not be suitable for some people including those with kidney or liver disease, folate deficiency (the elderly, chronic alcoholics, and people taking anticonvulsants are at risk of folate deficiency), glucose-6-phosphate deficiency, porphyria, severe allergies, thyroid dysfunction, or bronchial asthma. Therefore, BACTRIM will not prevent sequelae such as rheumatic fever. Symptoms may include: skin rash, fever, swollen glands, joint pain, muscle aches, severe weakness, pale skin, unusual bruising, or yellowing of your skin or eyes. Advertising revenue supports our not-for-profit mission. Others only trigger problems in specific types of G6PD deficiency. RxList does not provide medical advice, diagnosis or treatment. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. 7. ive missed three doses. Trimethoprim is metabolized in vitro to 11 different metabolites, of which, five are glutathione adducts and six are oxidative metabolites, including the major metabolites, 1-and 3-oxides and the 3-and 4-hydroxy derivatives. During treatment, ensure adequate fluid intake and urinary output to prevent crystalluria. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. information submitted for this request. In mice following oral administration of trimethoprim, no DNA damage in Comet assays of liver, kidney, lung, spleen, or bone marrow was recorded. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). P. jirovecii pneumonia in pregnancy is associated with preterm birth and increased morbidity and mortality for the pregnant woman. Review: The Pharmacology and Toxicology of Dofetilide. Naphthalene can also be in fumigants (pesticides), especially those used to keep snakes away. Weighing 40 kilograms (kg)4 teaspoonfuls (20 mL) of oral liquid or 2 tablets (or 1 DS tablet) 2 times a day for 10 days. Sulfamethoxazole and trimethoprim combination is best taken with a full glass (8 ounces) of water. Do not use Bactrim if you are pregnant. The usual adult dosage of Bactrim DS is 1 tablet every 12 hours, or 2 Bactrim tablets every 12 hours. Weighing 10 kg1 teaspoonful (5 mL) of oral liquid 2 times a day for 10 days. BACTRIM has been shown to be active against most isolates of the following microorganisms, both in in vitro and in clinical infections [see INDICATIONS AND USAGE]. Still, you should know common medications to avoid to prevent damage to your red blood cells. pale skin. These are common signs of infection. If you buy through links on this page, we may earn a small commission Heres our process. June 1980;92:762-769. If an infection isnt treated soon enough or cant be treated properly because the bacteria have become resistant to an antibiotic, abscesses can result. Drinking extra water will help to prevent some unwanted effects (eg, crystals in the urine). The artist will appreciate knowing so they can be on their guard, and maybe take extra precautions if necessary. Bacterial resistance is less likely to develop with Bactrim than if either ingredient (sulfamethoxazole or trimethoprim) is taken alone. The most common symptom of a tattoo infection is a rash or red, bumpy skin around the area of the tattoo. An in vitro chromosomal aberration test in human lymphocytes with sulfamethoxazole/trimethoprim was negative. The formulation of N 4-hydroxy metabolite is mediated via CYP2C9. The following serious adverse reactions are described elsewhere in the labeling: Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice. The overall prevalence of sulfite sensitivity in the general population is unknown. Like other drugs containing sulfonamides, BACTRIM can precipitate porphyria crisis and hypothyroidism. Keep using Bactrim even if your symptoms quickly improve. BACTRIM is contraindicated in pediatric patients less than two months of age [see CONTRAINDICATIONS]. Don't go to someone you know uses unsafe practices because nobody safe will give you one. This is not a complete list of items you should avoid if you have G6PD deficiency. If anything it will simply make it less likely for you to get an infection or anything like that. Keep from freezing. Certain medical conditions, such as kidney disease, If other medicines are being taken at the same time, Septra and Bactrim (sulfamethoxazole-trimethoprim). Tattoo-associated skin reactions. There may be an increased risk of severe adverse reactions in elderly patients, particularly when complicating conditions exist, e.g., impaired kidney and/or liver function, or concomitant use of other drugs. Healthline Media does not provide medical advice, diagnosis, or treatment. These doses are approximately 5 and 6 times the recommended human total daily dose on a body surface area basis. For treatment of bacterial infections: Adults1 tablet (DS tablet) of 800 milligrams (mg) of sulfamethoxazole and 160 mg of trimethoprim, 2 tablets of 400 mg of sulfamethoxazole and 80 mg of trimethoprim, or 4 teaspoonfuls or 20 milliliters (mL) of oral liquid every 12 hours for 10 to 14 days. Henna is a popular dye used for temporary tattoos and hair dye. An allergic reaction can also lead to anaphylactic shock. All of these 11 patients had normal renal function, and their ages ranged from 17 to 78 years (median, 60 years).11, Pharmacokinetic studies in children and adults suggest an age-dependent half-life of trimethoprim, as indicated in Table 5.12, Table 5: Half-life of Trimethoprim (TMP) in Pediatric Patients and Adults. MisterBearcat 8 yr. ago Advise pregnant women of the potential harm of BACTRIM to the fetus (see Clinical Considerations). This content does not have an English version. The following adverse reactions have been identified during post-approval use of BACTRIM. The antibiotics didn't effect the healing process, or how it looked after it healed, like I was worried about. Prescription drugs for acne can cause skin to be hyper-sensitive. Getting atattoocan be disastrous and lead to severe pain and scarring.