side effect of justicia carnea
This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Summer temperatures above 77 degrees Fahrenheit (25 C) are perfect. Ewe eje improves the production of white blood cells and other antibodies, all which are essential for strengthening immunity. Adetuyi is a Professor of Biochemistry in the Department of Chemical Sciences, Faculty of Sciences, Olusegun Agagu University of Science and Technology, Okitipupa, Ondo State, Nigeria. Venancio, E. T., Rocha, N. F., Rios, E. R., Feitosa, M. L., Linhares, M. I., Melo, F. H., Matias, M. S., Fonseca, F. N., Sousa, F. C., Leal, L. K., and Fonteles, M. M. Anxiolytic-like effects of standardized extract of Justicia pectoralis (SEJP) in mice: Involvement of GABA/benzodiazepine in receptor. and M.Sc. Although, medically, it is advised you see your doctor or a physician before using the leaf for medicinal uses. Rats were further observed for extended hours of 48h to see if mortality would occur. Ewe eje is an age-old herb medically proven to act as a blood tonic which can be attributed to its nutritional composition. The reference cuvette contained 2.95ml buffer, 0.03ml of substrate (epinephrine) and 0.02ml of water. When it comes to fertilizing, an NPK balance of 5-10-5 will work well, encouraging blooming and strong growth. The Justicia carnea leaves are rich in B-vitamins. Daily intake of the Ewe eje or ajeri can increase the absorption of iron and vitamins, Uses and health benefits of Ewe eje (Justicia carnea leaf). Hence, the use of Justicia carnea leaves may help reduce your risk of heart diseases, heart attack, stroke etc. Fitoterapia. Beijing: Chemical Press; 2011. While every effort has been made to describe these plants accurately, please keep in mind that height, bloom time, and color may differ in various climates. READ ALSO: How long does it take for Aju mbaise to work. Other English names for this plant include: flamingo flower, Jacobinia, Brazilian plume flower and Brazilian plume. Justicia carnea is affects Fertility according to a researched article published on ResearchgateJusticia carnea was found to lower sperm count Male Wistar Albino ratsthe effect of this herb on female fertility is not yet known. Justicia carnea [jus-TEE-see-ah, KAR-nee-uh] is popularly known as the Brazilian Plume Flower. Once the roots have established, adjust watering to three to five days apart. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. 2003;84:99104. However, watch out for nematodes and spider mites. This special leaf can be found around us- in our neighborhood. No observable focal sclerosis of renal glomeruli, capsular spaces around the glomerulus appears normal with distinct layering of renal microcellular structures. At the end of 14th day of administration, rats were allowed to fast overnight, sacrificed to collect samples for biochemical analysis and histopathological examination. Control treated group showed normal micromorphological sections. California Privacy Statement, As declared by all authors, no competing interests exist. This is in agreement with study of Anthonia et al., [21] who obtained LD50 above 5000mg/kg for aqueous extracts of J. carnea leaf. Group 2, 3, 4, 5, 6 were respectively administered orally with 50, 100, 500, 800 and 1200mg/kg body weight of JCEE once daily for 14days using an oral gavage. The effect of the ethanol extract of Justicea carnea (JC) leaves in phenylhydrazine induced-anemia albino rats on haematological and lipid profile parameters was investigated. Kone WM, Koffi AG, Bomisso EL, Tra Bi FH. . Water your plants deeply during growth periods, allowing the soil to dry . Google Scholar. From this study, the significant increase in platelet counts suggested that the extract could be useful in preventing excessive blood loss (through blood clotting) and resistance of capillary membranes to leakage of red cells when blood vessels are damaged. The renal cortex showed normal glomeruli with mesangial cells and capsular spaces appeared normal (white arrow), the renal tubules appear normal (blue arrow) and interstitial spaces also observed normal (black arrow). They also maintain our skin tone and texture, and help in reproductive functions. Allium satium and Justicia carnea either used alone or co-administered had an ameliorating effect on cadmium toxicity. With exception of low doses that showed normal morphology of the hepatocyte and sinusoid that is not infiltrated, high doses of extract greater than 500mg/kg showed mild fat congestion in the central venules with liver parenchyma showing area of hemorrhage compared to the control. Each rat was dissected and blood samples were collected by cardiac puncture using 5mL into tubes containing ethylenediaminetetraacetic acid (EDTA) for hematological analysis. Be careful about the moisture in the soil, avoiding letting it dry completely. The botanical name- Justicia carnea was coined after a scotish- James Justice, who happens to have found the plant first. These antibodies help prevent infections and fight off diseases. One of the symptoms of diabetes is elevated blood glucose level. He earned B.Sc. It has already been pointed out that this plant is used traditionally to boost blood production among the people of southern Nigeria. This is not a big concern as it wont kill the plant and you will find a solution at your local gardening center. Where, A=absorbance, TV=total volume, SV=sample volume, =extinction coefficient, TP=total protein. While histology of organs showed no adverse pathological lesions in the internal organs of rats, higher dose (1200mg/kg) over a period of time could cause noticeable liver and kidney injury. Hepatic and renal damage has been recently linked with the use of medicinal plants in the treatment of various diseases [5, 6]. The package will tell you exactly how, when, and how much feed to use. Justicia carnea is commonly cultivated and grown as an ornamental potted plant. The concentration of reduced glutathione content of the tissues was estimated according to Sedlak and Lindsay [19] method. Justicia carnea [jus-TEE-see-ah, KAR-nee-uh] is popularly known as the Brazilian Plume Flower. Justicia pectoralis seems to have antibacterial and anti-inflammatory effects. This claim by traditional healers with regard to the efficacy of justicia carnea in the treatment diabetes have been researched on and it was found to be true. A., Bezerra, G. A., Matos, F. J., and Viana, G. S. Antinociceptive, anti-inflammatory and bronchodilator activities of Brazilian medicinal plants containing coumarin: a comparative study. In a study conducted by Onyeabor and colleagues, the leaf extract of jusiticia carnea reverses the anemic effect of phenylhydrazine on the pack cell volume, red blood cell, and hemoglobin concentrations. There are several claims that justicia carnea can prevent epilepsy and convulsion among children. The effect of the ethanol extract of Justicea carnea (JC) leaves in phenylhydrazine induced-anemia albino rats on haematological and lipid profile parameters was investigated. Powdered sample was extracted using absolute ethanol and concentrated to obtain a slurry paste of J. carnea ethanol extracts. The spectacular rosy plumes of the flamingo-colored flower are distinctive and attract hummingbirds to pollinator gardens. 2008; 10:2. Google Scholar. what are the pros and cons of testosterone replacement therapy? Differences between means were considered to be significant at (p<0.05) using LSD (Least Square Difference) post hoc test. This information may not fit your specific health circumstances. Mounanga MB, Mewonob L, Angone SA. Be sure to follow relevant directions on product labels and consult your, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Mediterranean, Low-Fat Diets Are Best for Heart Problems, Least Amount of Exercise You Need to Stay Healthy, Nerve 'Pulse' Therapy May Help Ease Sciatica, New Book: Take Control of Your Heart Disease Risk, MINOCA: The Heart Attack You Didnt See Coming, Health News and Information, Delivered to Your Inbox. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. Furthermore, increased MID by the extracts could indicate macrophage formation ability and pathogenic scavenging role. View abstract. The perennial plant puts on a never-ending show of radiant flowers from early spring to fall. Information from this source is evidence-based and objective, and without commercial influence. Correspondence to Cookies policy. Justicia carnea is a medicinal plant that is used conventionally as blood tonic from time immemorial in Nigeria. Chariandy, C. M., Seaforth, C. E., Phelps, R. H., Pollard, G. V., and Khambay, B. P. Screening of medicinal plants from Trinidad and Tobago for antimicrobial and insecticidal properties. Aim. Make sure to follow the package instructions carefully. J. Appl. When properly cooked with water, the leaf resembles blood, and when milk is added, it turns pink. Filed in Biochemistry Project Topics, Current Projects by TMLT Editorials on September 22, 2020. It also increases good cholesterol levels. Different drugs are used but many depend mainly on plants and herbal products for its treatment. The significant increase in MDA level at 1200mg/kg might be due to the presence of active secondary metabolites in the extracts that could have acted as prooxidant. The levels of white blood cell count, lymphocyte, granulocyte and MID could indicate that ethanol extract of J. carnea leaf pose no toxicity or sub acute inflammation to the overall defense mechanism and immunity of the experimental rats. The appropriate dose of Justicia pectoralis depends on several factors such as the user's age, health, and several other conditions. Keep an eye out for glasshouse red spider mite and glasshouse whitefly. This post was last modified on January 2, 2023 5:23 pm. Phytochemical screening and Gas Chromatography-Mass Spectrometry (GC-MS) analysis indicated presence of . 1999;9:18. The lush foliage and distinctive flowers make Brazilian Plume a natural for a . You can add the leaves and water altogether in a pot and allow to boil till the water turns red. How Justicia Betonica is effective for various diseases is listed in repertory format. The genus Justicia named after the 18th-century Scottish botanist James Justice is a flowering plant in the family Acanthaceae. Authors KOK and ESA performed the statistical analysis and managed the analyses of study. In this article i will take you through the nutritional and medicinal benefits of justicia carnea. 1958;25(1):192205. Akintimehin, E.S., Karigidi, K.O., Omogunwa, T.S. Justicia carnea does not cause miscarriage or congenital birth defects. Materials and Methods Plant material Justicia carnea leaves used in this study were collected from Ozalla Isuofia in Anambra State and identified by Mr. Ozioko They look terrific in properly shaded outside areas such as porches, patios, driveways, and entryways. We currently have no information for JUSTICIA PECTORALIS overview. In this study, nutritive potentials and effects of aqueous extract of Justicia carnea leaves on biochemical indices of anaemic male Wistar albino rats were investigated. Related: The Persian Shield plant is also in the Acanthaceae family. Philadelphia: WB. The plant is hardy to USDA Hardiness Zones 8b through 11. Nunes TRS, Cordeiro MF, Beserra FG, et al. Significant (P<0.05) decrease observed in liver total protein of rat administered with 1200mg/kg of extract could be due to intrinsic factors in-vivo that might not necessarily indicate adverse reaction of the extracts. Too much fertilizer is damaging for your plant. hindawi publishing corporation evidence-based complementary and alternative medicine. Biochem Pharmacol. However, the mechanism by which phytochemicals act as prooxidants in-vivo is still under investigation [25]. Previously, J. carnea leaf has been reported to contain high quantity of phytochemical constituents (such as saponins, alkaloids and terpenoids), vitamins (A, C and E) and minerals [9, 10]. Side effects of Ewe eje (Justicia carnea leaf Side Effects) Ewe eje is safe and healthy for consumption. Justicia pectoralis is a flowering herb that grows in tropical areas of the Americas, including South and Central America. Walters DM., Cho Hye-Youn, Kleeberger SR. Oxidative Stress and Antioxidants in the Pathogenesis of Pulmonary Fibrosis: A Potential Role for Nrf2. Tips on how to get rid of leaf eating caterpillar. Exactly 1.0ml of tissues (liver and kidney) was deproteinised using 0.1ml of 10% TCA and centrifuged at 650g for 5min to obtain supernatant. Nutritive properties of aqueous extract Justicia carnea leaves and its effects on haematological and some biochemical indices of anaemia induced male wistar albino rats. CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. In-vivo studies have revealed that radicals produced from these dietary antioxidants are constantly regenerated back to their active form by GSH in the ascorbate glutathione cycle. The compound responsible for this activity is lignan. It may be, judging from the antidepressant activity of other plant of justicia species whose activity have been studied, proper to state that justicia carnea may possess antidepressant properties. Olumese FE, Onoagbe IO, Eze GI, Omoruyi FO. SOD is involved in the dismutation of the highly reactive superoxide anion to molecular oxygen (O2) and to less reactive hydrogen peroxides (H2O2) species, whereas CAT removes hydrogen peroxide (H2O2) and toxic hydroxyl radical into water molecule [35]. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. Karigidi is a lecturer in the Biochemistry unit of Chemical Sciences Department, Olusegun Agagu University of Science and Technology, Okitipupa, Ondo State, Nigeria. Recently, it has also been reported that the species possess cardioprotective properties, antioxidant and are generally rich in vitamins and minerals [10,11,12]. Tietz NW. However, there have not been scientific backing on this claim, yet, from the antiviral properties of other species of justicia, it could be that this plant possess antiviral properties which is utilized in the treatment of hepatitis infection. The animals were allowed free access to rat chow and water ad libitum. 1972;47:38994. Relative to the control, liver of rats treated with doses of J. carnea ethanol extract showed varied degree of hepatic injury in a dose dependent manner. 1. Ashwagandha tea: 10 benefits, side effects and recipes, 7 interesting health facts about Black sapote fruits. Tissues were stained with haematoxylin and eosin, mounted on glass slides and examined under a standard light microscope. When it comes to blood boosting and treatment of anemia, justicia carnea has proven beyond doubt to be an effective remedy. Ogbe RJ, Adoga GI, Abu AH. Ewe eje is safe and healthy for consumption. 400). Use liquid fertilizers, slow-release or granulated formulas. This leaf replenishes your blood supply immediately. The animals were randomly distributed into cages and allowed to acclimatize for 2 weeks in a well ventilated room under natural lighting condition. Pot the specimen and bring it indoors to add a bright touch of color to your interiors. All authors read and approved the final draft of the manuscript. -Amylase binding-interaction with JCAE was also investigated using fluorescence spectroscopy and molecular docking. Each of the rats received 1500, 2900 and 5000mg/kg body weight of JCEE respectively and examined within 24h for manifestation of toxicity. 5. https://doi.org/10.1016/j.jep.2007.02.011. While graded doses of J. carnea ethanol extract showed no significant difference in the liver and kidney GSH compared to the control, only rats that received 1200mg/kg body weight JCEE statistically decreased in the kidney. View abstract. Oso BJ, Oyewo EB and Oladiji AT. This may be because of its hepatoprotective activity. Onoagbe IO, Attah V, Luther MM, Esekheigbe A. Hypoglycemic and anti-diabetic effects of Morinda lucida and Tetracera alnifora in normal and streptozotocin-induced diabetic rats. Two of the most important soil considerations include fertility and drainage. In these groups, from mild to severe order; shows observable congested portal vein, the liver parenchyma showed area of harmorrhage, the morphology of the hepatocytes appear pyknotic, some show mild fat infiltration (red arrow) the sinusoids appear fibrotic with infiltration of inflammatory red cells (red arrow). B-vitamins are good sources of energy. This is due to the inability of the pancreatic beta cells to secrete insulin, which transports glucose to cells, or the inability of cells of the body to recognize insulin. Local consumers of the leaves are mostly . Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. Note: A=change in absorbance, TV=total volume, SV=sample volume, =molar extinction=4020M1cm1, TP=total protein. PubMed Central Superoxide dismutase (SOD) activities were elevated across all doses in the liver with significant (p<0.05) difference only observed in the highest dose (1200mg/kg) while kidney showed no significant difference compared to the control. Afr J Tradit Complement Altern Med. Justicia carnea (Brazilian Plume) is an upright, evergreen shrub with large, dark green leaves, 10 in. Photomicrograph of liver sections stained with haematoxylin and eosin (H & E) are presented in Fig. Vitamin B aids in the formation of red blood cells and helps to build tissues. A total number of forty two (42) male albino rats weighing between 120 and 170g were used in this study. The blood stimulating effects could be due to the presence of dietary bioactive constituents that stimulate activities of haematopoietic cells and stabilization of blood in circulation [21]. J Ethnopharmacol. Pinch Justicia carnea plants back after theyve flowered. Despite the avalanche use of medicinal plant, preliminary toxicity studies remain essential tools to ensure safe consumption and prevent unexpected toxicity that could arise from long term exposure. volume7, Articlenumber:2 (2021) Backfill the soil gently, filling the empty space around the root ball and then press it down with your hands. For a few weeks, the cutting should be watered every day to promote root development. Justicia carnea needs bright, indirect light to thrive. 3 The plants in the family are reported to have CNS effects which are exploited in the management of epilepsy, other mental disorders, headache and fever, probably due to their sedative and analgesic properties. Liver superoxide dismutase (SOD) activity was significantly (p<0.05) increased at 1200mg/kg while other tested doses caused no detrimental effect on glutathione, catalase, SOD and malondialdehyde level in liver and kidney. Several medicinal plants such as Xylopia aethiopica [25], Tectona grandis [26] and extracts of M. indica, A. hybridus and T. occidentalis [27] have also been reported to elevate RBC, hemoglobin and packed cell volume. The present study investigated the antioxidant and in vitro antidiabetic capacities of Justicia carnea aqueous leaf extract (JCAE) using -amylase inhibition model. (2020). Corra, GM., de C. Alcntara, AF. These tropical plants are not very fussy about soil. We use cookies on this website, you can read about them here. Blooming from early summer to fall, the flowers are attractive to hummingbirds and butterflies. White blood cell counts usually increases following foreign invaders (pathogens) resulting in normal body physiological response which boost the bodys defense mechanisms [28, 29]. 34-45. Onyeabo C, Achi NK, Ekeleme-Egedigwe CA, Ebere CU, Okoro CK. 15 Amazing benefits of brocoli juice and side effects. The Health benefit of Ewe eje (Justicia carnea leaf) are highlighted in this article. This encourages better flowering and bushier and denser new growth. This study investigated the in-vitro antioxidant activity of ethanol leaf extract of Justicia carnea and its effect on antioxidant status of alloxan-induced diabetic albino rats. Side Effects, Uses and Health benefits of Ewe eje (Justicia carnea leaf), The exact topic of this article first appeared on www.nimedhealth.com.ng. Feed the soil when the cutting is new to encourage better growth. However, lowest (50mg/kg) dose of extract significantly elevated MCH and MCHC. Medapa S, Singh GRJ, Ravikumar V. The phytochemical and antioxidant screening of Justicia wynaadensis. These compounds beyond boosting your blood concentration, thereby enhancing the transport of nutrients to various parts of the body, also boost your immune system against several infectious diseases. Pompella A, Visvikis A, Paolicchi A, De Tata V, Casini AF. While vitamin A maintains good vision, vitamin B are good for cellular functions such as metabolisms and energy production, and improve brain functioning. There should be further studies on the antidepressant activity of justicia carnea leaves. Clinical Guide to Laboratory tests. The result of hematology indices is presented in Table3. Contamination of medicinal plant could be as a result of contaminants (such as heavy metals, aflatoxin and pathogenic microbes) from soil and manner of herbal preparations [4]. Create a beautiful garden with this colorful and Use our interactive toolsto design your dream garden. However, caution should be taken as higher dose at 1200mg/kg could cause noticeable tissue injury. Details on Purple Shield plant care. Article Wash the Justicia carnea leaves thoroughly to eliminate all forms of insects and dust. Google Scholar. Mr. K.O. Research reports it isn't capable of . It is very rich in iron, a major component is RBC hemoglobin. As reported by science, Justicia carnea is composed of secondary metabolites such as: flavonoids, terpenoids, alkaloids, phenols, saponins and tannins. Prof. F.O. PubMedGoogle Scholar. One of the side-effects of some orthodox drugs used in the past had been excessive inhibition of the carbohydrate-hydrolyzing enzymes, which in turn leads to abdominal discomfort and. The non significant decrease observed in this study is in consonance with the work of Onyeabo et al., [9] who also reported no significant difference in the relative weights of liver and kidney. Materials and Methods Justicia carnea is a popular ornamental plant, which possesses powerful medicinal values. The efficiency of some preexisting anti-obesity drugs was limited by several adverse effects associated with them including gastrointestinal disorder, high risk of cancer, and long-term use detrimental effects on some organs such as liver, kidney and pancreas [ 4, 8 ]. de Vries, J. X., Tauscher, B., and Wurzel, G. Constituents of Justicia pectoralis Jacq. These compositions (metabolites and nutrients) are all responsible for the medicinal value and the health benefits of Justicia carnea. This is . Studies have also confirmed this claim. Cut from the stem, some fresh or dried Justicia carnea leaves. The effect of the ethanol extract of Justicea. Further study assessing the kidney indices (urea, creatinine and electrolytes) is however encouraged to ascertain the safety of the plant extract on renal function. As a consequence, depletion of reduced glutathione (GSH) either by removal from the cell or oxidation to GSSG could eventually lead to mild oxidative stress in cells and tissues [33, 34]. https://doi.org/10.4314/njps.v19i1.32627. Consequently, the effects of the extract on MDA level could indicate damage to cell membrane lipids of the hepatocyte which could result to increased generation of reactive oxygen species (ROS). Section of livers and kidneys were excised and fixed in 10% formalin for histopathology examination. It is commonly referred to as blood root, blood booster, ewe eje in Yoruba, Ogwu obara in Igbo, and jacobinia in Brazil and south America.The plant, which is usually green in color and produces pink flowers, belongs to the family of Acanthaceae.